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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SETD1B
All Species:
21.52
Human Site:
T1735
Identified Species:
36.41
UniProt:
Q9UPS6
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UPS6
NP_055863.1
1923
208732
T1735
T
D
E
P
P
A
D
T
Q
G
M
S
I
P
A
Chimpanzee
Pan troglodytes
XP_523492
1707
185692
V1524
S
A
R
Q
L
E
G
V
D
T
Q
G
T
N
R
Rhesus Macaque
Macaca mulatta
XP_001092031
624
66545
P451
E
P
L
A
K
E
R
P
G
T
P
P
G
P
P
Dog
Lupus familis
XP_543382
1925
209302
T1737
T
D
E
P
P
A
D
T
Q
G
M
S
I
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8CFT2
1985
215333
T1797
T
D
E
P
P
M
D
T
Q
G
M
S
I
P
A
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510235
695
75024
L522
L
K
E
Q
R
T
K
L
P
F
F
S
E
R
D
Chicken
Gallus gallus
Q5F3P8
2008
223067
T1820
A
E
E
P
P
A
D
T
Q
G
M
S
I
P
A
Frog
Xenopus laevis
Q66J90
1938
216239
T1750
A
D
E
P
P
I
D
T
Q
G
K
S
I
P
A
Zebra Danio
Brachydanio rerio
Q1LY77
1844
204122
T1658
S
E
E
P
D
V
D
T
Q
G
K
S
I
P
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001015221
1641
188364
G1467
K
L
I
S
K
M
Q
G
I
S
R
E
A
R
S
Honey Bee
Apis mellifera
XP_395451
1406
159180
L1233
L
T
G
K
M
Q
A
L
S
R
E
A
R
S
N
Nematode Worm
Caenorhab. elegans
Q18221
1507
171664
L1334
T
A
I
R
H
Q
H
L
A
S
K
D
M
R
L
Sea Urchin
Strong. purpuratus
XP_791552
1963
220543
S1774
V
Q
E
S
V
T
D
S
S
A
L
D
E
S
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q8X0S9
1313
145607
N1140
S
R
A
N
R
V
N
N
R
R
Y
V
A
E
I
Conservation
Percent
Protein Identity:
100
37.3
27.9
91.9
N.A.
87.7
N.A.
N.A.
23.1
61.5
55
51
N.A.
24.7
23.9
22.3
21.3
Protein Similarity:
100
50.3
28.8
93.9
N.A.
90.2
N.A.
N.A.
26.7
71.1
66.6
63.6
N.A.
39.4
38.6
35.2
35.2
P-Site Identity:
100
0
6.6
100
N.A.
93.3
N.A.
N.A.
13.3
86.6
80
66.6
N.A.
0
0
6.6
13.3
P-Site Similarity:
100
6.6
6.6
100
N.A.
93.3
N.A.
N.A.
13.3
93.3
80
80
N.A.
6.6
6.6
13.3
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
22.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.4
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
8
8
0
22
8
0
8
8
0
8
15
0
43
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
29
0
0
8
0
50
0
8
0
0
15
0
0
8
% D
% Glu:
8
15
58
0
0
15
0
0
0
0
8
8
15
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
8
8
8
43
0
8
8
0
0
% G
% His:
0
0
0
0
8
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
15
0
0
8
0
0
8
0
0
0
43
0
8
% I
% Lys:
8
8
0
8
15
0
8
0
0
0
22
0
0
0
0
% K
% Leu:
15
8
8
0
8
0
0
22
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
8
15
0
0
0
0
29
0
8
0
0
% M
% Asn:
0
0
0
8
0
0
8
8
0
0
0
0
0
8
8
% N
% Pro:
0
8
0
43
36
0
0
8
8
0
8
8
0
50
8
% P
% Gln:
0
8
0
15
0
15
8
0
43
0
8
0
0
0
0
% Q
% Arg:
0
8
8
8
15
0
8
0
8
15
8
0
8
22
8
% R
% Ser:
22
0
0
15
0
0
0
8
15
15
0
50
0
15
8
% S
% Thr:
29
8
0
0
0
15
0
43
0
15
0
0
8
0
8
% T
% Val:
8
0
0
0
8
15
0
8
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _